Concentric demyelination pattern in COVID-19-associated acute haemorrhagic leukoencephalitis: a lurking catastrophe?
نویسندگان
چکیده
منابع مشابه
Acute Haemorrhagic Leukoencephalitis: Report of a Case
Acute haemorrhagic leukoencephalitis (AHL) usually involves the subcortical white matter but spares the cerebral cortex and subcortical U fibers. The outcome is usually fatal and very few survivors have been reported after decompressive therapy. An unusual presentation of a prolonged course of AHL in a 39-year-old man is reported. Initial brain magnetic resonance images (MRI) showed an irregula...
متن کاملEarly and widespread injury of astrocytes in the absence of demyelination in acute haemorrhagic leukoencephalitis
Acute hemorrhagic leukoencephalitis (AHL) is a fulminant demyelinating disease of unknown etiology. Most cases are fatal within one week from onset. AHL pathology varies with the acuteness of disease. Hemorrhages, vessel fibrinoid necrosis, perivascular fibrin exudation, edema and neutrophilic inflammation are early features, while perivascular demyelination, microglial foci and myelin-laden ma...
متن کاملLeukoencephalitis and vasculitis with perivascular demyelination in a Weimaraner dog.
Aseptic and noninfectious diseases of the central nervous system are being recognized with increasing frequency. After multiple episodes of neurologic illness, this 7-year-old Weimaraner dog was euthanatized and submitted for postmortem examination. Lesions in the central nervous system were found mainly in the white matter of the cerebral cortex and cervical spinal cord and represented acute a...
متن کاملFavourable Outcome in a 33-Year-Old Female with Acute Haemorrhagic Leukoencephalitis
BACKGROUND Acute haemorrhagic leukoencephalitis (AHLE) is a rare and rapidly fatal disease of unknown aetiology. There is a paucity of literature on the presentation and management of this rare disease. CASE DESCRIPTION We report the case of a 33-year-old female presenting with headache and left-sided apraxia. Imaging revealed a right-sided white matter lesion with extensive cytotoxic oedema....
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On March 11, 2020, the World Health Organization (WHO) announced the pandemic outbreak of coronavirus disease 2019 (COVID-19), due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which began in December 2019 in Wuhan, China (1). Iran was the 25th country affected by COVID-19. According to the Iranian Ministry of Health, every 12 minutes, one person dies in Iran because of CO...
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ژورنال
عنوان ژورنال: Brain
سال: 2020
ISSN: 0006-8950,1460-2156
DOI: 10.1093/brain/awaa375